Dra. Gabriela Rodríguez Manzo



Ph.D.: Pharmacology, Cinvestav, 1996

M. Sc.: Psychobiology, UNAM, 1984

B. Sc.: Biology, Universidad Autónoma Metropolitana, 1981

Current Position: Professor 3D at CINVESTAV

Member of the National System of Researchers (SNI): Level III


Research Lines:

Pharmacology and physiology of male sexual behavior

Pharmacological and physiological analysis of the sexual exhaustion phenomenon 

Sexual activity and brain plasticity

Animal models of sexual dysfunction


Selected publications


Peer-reviewed papers:

González-Morales E., Rodríguez-Manzo G. (2020). Endocannabinoids mediate long-lasting behavioural and physiological changes in male rats induced by the repeated activation of the mesolimbic system by copulation to satiety. Behav. Brain Res. 383:112510 https://doi.org/10.1016/j.bbr.2020.112510 Corrigendum: https://doi.org/10.1016/j.bbr.2020.112572

Canseco-Alba A., Rodríguez-Manzo, G. (2019). Endocannabinoids interact with the dopaminergic system to increase sexual motivation: Lessons from the sexual satiety phenomenon. Front. Behav. Neurosci. 13: art. number 184. https://doi.org.10.3389/fnbeh.2019.00184

Guadarrama-Bazante, I.L., Rodríguez-Manzo, G. (2019). Nucleus accumbens dopamine increases sexual motivation in sexually satiated male rats. Psychopharmacology 236: 1303-1312. https://doi.org/10.1007/s00213-018-5142-y

Soria-Violante V., Cruz S.L., Rodríguez-Manzo, G. (2019). Sexual behaviour is impaired by the abused inhalant toluene in adolescent male rats. Eur. J. Neurosci. 50: 2113–2123. https://doi.org/10.1111/ejn.13969

Garduño-Gutiérrez R., León-Olea M., Rodríguez-Manzo G. (2018) Opioid receptor and β-arrestin2 densities and distribution change after sexual experience in the ventral tegmental area of male rats. Physiol Behav 189: 107–115. http://dx.doi.org/10.1016/j.physbeh.2018.03.019

Rodríguez-Manzo, G. and Canseco-Alba, A. (2015). Biphasic effects of anandamide on behavioural responses: emphasis on copulatory behaviour. Behav Pharmacol, Special issue: Pharmacological Approaches to the Study of Social Behaviour, 26: 607–615. http://dx.doi.org/10.1097/FBP.0000000000000154

Book chapters:

Rodríguez-Manzo, G., Canseco-Alba A. (2020) Endocannabinoids. In: Lykins AD (ed), Encyclopedia of Sexuality and Gender. Springer Nature. https://doi.org/10.1007/978-3-319-59531-3_53-1

Hull, E.M., Rodríguez-Manzo, G. (2017). Male Sexual Behavior. In: Pfaff, D.W and Joëls, M. (editors-in-chief). Hormones, Brain, and Behavior, 3rd edition, Vol 1. Oxford: Academic Press/Elsevier; pp. 1–57. ISBN 978-0-12-803592-4 http://dx.doi.org/10.1016/B978-0-12-803592-4.00001-8

Hull EM, Rodríguez-Manzo G. (2017). Male Sexual Behavior. In: Reference Module in Neuroscience and Biobehavioral Psychology. Chap. 35. Elsevier Science. pp. 1-10. ISBN 9780128093245. http://dx.doi.org/10.1016/B978-0-12-809324-5.00350-3 

Rodríguez-Manzo G, Canseco-Alba A. (2014). A role for learning and memory in the expression of an innate behavior: the case of copulatory behavior. In: Identification of Neural Markers Accompanying Memory. Meneses A (Ed). Elsevier Insights; Elsevier, p.p. 135-147. ISBN: 978-0-12-408139-0 http://dx.doi.org/10.1016/B978-0-12-408139-0.00009-2


Laboratory 18


Phone +52(55)5483-2871

Fax +52(55)5483-2863

E-mail: grodrigu@cinvestav.mx