Dra. Carolina López Rubalcava

PhD: in Pharmacology (Departamento de Farmacología y Toxicología, Centro de Investigación y de Estudios Avanzados del I.P.N. México, D.F., México, 1995).

B.Sc.: in Biology (Facultad de Ciencias, Universidad Nacional Autónoma de México, México, D.F., México, 1990).

Current position: Professor 3C at the Pharmacobiology Department. Center for Research and Advanced Studies. Mexico, D.F.

Member of the National System of Researchers (SNI): Level II

Research interests

  • Behavioral pharmacology
  • Neurobiology of anxiety and depression
  • Neurobiology of stress and its relationship with psychiatric disorders
  • Mechanism of action of antidepressant and antianxiety medications
  • Phytopharmacology


Representative publications

* Páez-Martinez N, Aldrete-Audiffred J, Gallardo-Tenorio A, Castro-Garcia M, Estrada-Camarena E, Lopez-Rubalcava C (2013) Participation of GABA(A), GABA(B) receptors and neurosteroids in toluene-induced hypothermia: Evidence of concentration-dependent differences in the mechanism of action. Eur J Pharmacol. 698(1-3):178-85.

* Martínez-Vázquez M, Estrada-Reyes R, Martínez-Laurrabaquio A, López-Rubalcava C, Heinze G. (2012) Neuropharmacological study of Dracocephalum moldavica L. (Lamiaceae) in mice: sedative effect and chemical analysis of an aqueous extract. J Ethnopharmacol. 2012 Jun 14; 141(3):908-17.

* Estrada-Camarena E, López-Rubalcava C, Hernández-Aragón A, Mejía-Mauries S, Picazo O. (2011) Long-term ovariectomy modulates the antidepressant-like action of estrogens, but not of antidepressants. J Psychopharmacol. 2011 Oct; 25(10):1365-77.

* Mostalac-Preciado CR, de Gortari P, López-Rubalcava C. (2011) Antidepressant-like effects of mineralocorticoid but not glucocorticoid antagonists in the lateral septum: Interactions with the serotonergic system. Behav Brain Res. 223(1):88-98.

* Rogel-Salazar G, López-Rubalcava C. (2011) Evaluation of the anxiolytic-like effects of clomipramine in two rat strains with different anxiety vulnerability (Wistar and Wistar-Kyoto rats): participation of 5-HT1A receptors. Behav Pharmacol. 22(2):136-46.


Laboratory 7

Phone: +52(55)5483-2872
Fax +52(55)5483-2863
E-mail: clopezr@cinvestav.mx