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  • 28 / 04 / 2017
Cinvestav - Centro de Investigación y de Estudios Avanzados del I.P.N.

Dra. Norma Leticia Gómez Viquez

Post-doctoral research fellow: University of Maryland Biotechnology Institute, 2004-2007.

Ph.D. Degree: Physiology, Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del I.P.N. México, D.F., México, 2003.

M.Sc. Degree: Physiology, Departamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del I.P.N. México, D.F., México, 1997.

B.Sc. Degree: Pharmacist (Químico Farmacéutico Industrial), Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional. México, D.F., México, 1994.

Current Position: Professor 3A.

Member of the National System of Researchers (SNI): Level I

Lines of Research:

Research in my laboratory is directed towards understanding the roles of calcium signaling in the function and dysfunction of cardiac cells. In particular, to identify the molecular causes of:

  • Cardiac diastolic and systolic dysfunction in metabolic syndrome
  • Left ventricular hypertrophy in hipertension     
  • Atrial and ventricular arrhythmias in metabolic sysndrome and hypertension

To this end, we apply fluorescence Ca2+ imaging, molecular biology, electrophysiology and microflurometry.

 

Representative publications:

* Ramos-Mondragón R, Galindo CA, García-Castañeda M, Sánchez-Vargas JL, Vega AV, Gómez-Viquez NL, Avila G. Chronic potentiation of cardiac L-type Ca(2+) channels by pirfenidone. Cardiovascular Research 96(2):244-54. 2012.

* Hong E, Larios F, Gómez-Viquez NL, Huang F, Bravo G. Role of alpha adrenoceptors and nitric oxide on cardiovascular responses in acute and chronic hypertension. J Physiol Biochem 67(3):427-35. 2011.

* Gómez-Viquez NL, Guerrero-Serna G, Arvizu F, García U, Guerrero-Hernández A. Inhibition of SERCA pumps induces desynchronized RyR activation in overloaded internal Ca2+ stores in smooth muscle cells. Am J Physiol Cell Physiol 298(5):C1038-46. 2010.

* Ziman AP, Gómez-Viquez NL, Bloch RJ, Lederer WJ. Excitation-contraction coupling changes during postnatal cardiac development. J Mol Cell Cardiol 48(2):379-86. 2010.

* Guatimosim S, Amaya MJ, Guerra MT, Aguiar CJ, Goes AM, Gómez-Viquez NL, Rodrigues MA, Gomes DA, Martins-Cruz J, Lederer WJ, Leite MF. Nuclear Ca2+ regulates cardiomyocyte function. Cell Calcium. 44(2):230-42. 2008.


Laboratory  2

Technical support:

Maritza Mayorga Luna ( mayorga_99@yahoo.com )

Phone: +52(55)5483-2879
Fax +52(55)5483-2863
e-mail: nogomez@cinvestav.mx

Cinvestav | Centro de Investigación y de Estudios Avanzados del I.P.N.
Av. Instituto Politécnico Nacional 2508, Col. San Pedro Zacatenco, C.P. 07360 México, D.F. Apartado postal: 14-740, 07000 México, D.F.
Teléfono: 5747 3800
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